eustar  —  european scleroderma trials and research


EUSTAR Basic Research: Ongoing Projects

Project ID Principal Investigator Title Project Status
Y. Allanore VEGF Published in Ann Rheum Dis 2006
BP02 B. Cronstein Adenosine receptors: Fibroblasts non involved skin vs. involved skin  
BP03 O. Distler Expression profile of subcutaneous fat tissue biopsies Manuscript in preparation
BP04 R. Sfrent-Cornateanu Interleukin 6 polymorphisms and systemic sclerosis: results from a multicenter EUSTAR study of European Caucasian patients Submitted to Journal of Autoimmunity
BP05 T. Radstake Genetic factors in the susceptibility and phenotype of systemic sclerosis Submitted to the board
BP06 O. Kowal-Bielecka Single nucleotide polymorphisms (SNPs) of the gene encoding arachidonate 5-lipoxygenase activating protein (ALOX5AP, 5-lipoxygenase activating protein FLAP) in patients with systemic sclerosis (SSc) - EUSTAR based study Sent to the centres on 21/07/2008
BP07 O. Distler TNF-alpha inhibitor therapy questionnaire Submitted for publication
BP08 T. Medsger
C. Feghali Bostwick
Genome wide association study (GWAS) Submitted to the board
BP09 S. Guiducci RANK, RANKL and OPG polymorphisms in Systemic Sclerosis Submitted to the board
BP10 Y. Allanore Unraveling genetic background of systemic sclerosis associated pulmonary arterial hypertension Approved by the board
BP11 F. Indiveri,
G. Filaci
Analyses on alterations present in SSc concerning oxidative stress and immune regulation Submitted to the board